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    Pinometostat (EPZ5676)
    Pinometostat (EPZ5676)
    Catalog No： V0378
    CAS No. (CAS Registry Number)： 1380288-87-8
    Description: Pinometostat (formerly also known as EPZ-5676) is a novel and potent small molecule S-adenosyl methionine (SAM) competitive inhibitor of protein methyltransferase DOT1...
    EPZ005687
    EPZ005687
    Catalog No： V0379
    CAS No. (CAS Registry Number)： 1396772-26-1
    Description: EPZ005687 is a novel, potent and selective inhibitor of EZH2 with Ki of 24 nM in a cell-free assay, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein...
    GSK343
    GSK343
    Catalog No： V0380
    CAS No. (CAS Registry Number)： 1346704-33-3
    Description: GSK343 is a novel, highly potent and selective H3-lysine 27 (H3K27) methyltransferase EZH2 inhibitor with IC50 of 4 nM in a cell-free assay, it showed 60 fold selectivity against EZH...
    BIX 01294
    BIX 01294
    Catalog No： V0381
    CAS No. (CAS Registry Number)： 935693-62-2 (free base);
    Description: BIX01294 is a novel and potent inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM in a cell-free assay. BIX-01294 was discovered by screening a library of 125,000 synthetic an...
    Tazemetostat (EPZ-6438)
    Tazemetostat (EPZ-6438)
    Catalog No： V0382
    CAS No. (CAS Registry Number)： 1403254-99-8
    Description: Tazemetostat (formerly known as EPZ-6438 or E7438) is an oral, potent, and selective EZH2 inhibitor with Ki and IC50 of 2.5 nM and 11 nM in cell-free assays. Mutations within the catalyti...
    SGC707
    SGC707
    Catalog No： V0383
    CAS No. (CAS Registry Number)： 1687736-54-4
    Description: SGC707 is a novel, potent, selective and cell-active allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3) with IC50 and Kd of 31 nM and 53 nM, respectively. PRMT3 is&...
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