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    Catalog No: V0293
    CAS No. (CAS Registry Number): 808118-40-3
    Description: FG-4592 (also known as ASP1517 and Roxadustat) is a novel, orally bioavailable and potent small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PH), an enzyme up-re...
    Catalog No: V0294
    CAS No. (CAS Registry Number): 362-07-2
    Description: 2-Methoxyestradiol (also known as 2-MeOE2; 2-ME) is an endogenous and orally bioavailable estradiol metabolite of 17β-estradiol (E2) with anticancer activity, it is an inhibitor of m...
    Catalog No: V0295
    CAS No. (CAS Registry Number): 931398-72-0
    Description: IOX2 is a novel and potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM in a cell-free assay, it exhibits 100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or...
    Catalog No: V0296
    CAS No. (CAS Registry Number): 1227158-85-1
    Description: BAY 87-2243 is a novel, highly potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1) which inhibits HIF-1 reporter gene activity and CA9 protein expression with IC50 of 0.7...
    Catalog No: V0297
    CAS No. (CAS Registry Number): 685898-44-6
    Description: PX-478 is a novel, potent and orally bioactive small molecule HIF-1α (hypoxia-inducible factor-1α) inhibitor with potential antitumor activity. The mechanism of action of PX-478 has yet t...
    Catalog No: V0298
    CAS No. (CAS Registry Number): 223387-75-5
    Description: FG-2216 (also known as YM311; IOX3; YM-311) is a novel, potent, and orally bioactive HIF prolyl 4-hydroxylase (PHD) inhibitor with IC50 of 3.9 μM for PHD2.  FG-2216 is orally bi...
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