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    Catalog No: V2904
    CAS No. (CAS Registry Number): 1361224-53-4
    Description: AMG-3969 is a potent, novel and metabolically stable disruptor of glucokinase-glucokinase regulatory protein interaction (GK-GKRP) with IC50 of 4 nM. AMG-396...
    Catalog No: V4556
    CAS No. (CAS Registry Number): 1215197-37-7
    Description: PF-04991532 is a novel, potent, hepatoselective glucokinase activator with EC50 of 80 and 100 nM in human and rat, respectively. It is able to ameliorate hypergly...
    Catalog No: V13883
    CAS No. (CAS Registry Number): 300353-13-3
    Description: Ro 28-1675 (Ro-0281675) is a novel, potent and allosteric GK activator with a SC1.5 value of 0.24± 0.0019 uM. Ro 28-1675 reduced fasting and postprandial glucose levels following an ...
    Catalog No: V20192
    CAS No. (CAS Registry Number): 1191995-00-2
    Description: Dorzagliatin (RO-5305552; HMS-5552; sinogliatin) is an investigational antidiabetic agent acting as a dual-acting glucokinase activator (GKA) that is able to improves ...
    Catalog No: V25611
    CAS No. (CAS Registry Number): 1137916-97-2
    Description: MK-0941 mesylate, the mesylate salt of MK0941, is a novel, orally bioactive and allosteric glucokinase activator (GKA) with anti-diabetic effects. It activates glucokinase with EC50s...
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