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    Catalog No: V1946
    CAS No. (CAS Registry Number): 328998-25-0
    Description: 4E1RCat is a potent and dual inhibitor of eIF4E:eIF4G and eIF4E:4E-BP1 protein-protein interaction, and also inhibits the binding of eIF4G to eIF4E with IC50 of 3.2 μM. 4E1RCat preve...
    Catalog No: V1959
    CAS No. (CAS Registry Number): 315706-13-9
    Description: 4EGI-1 is a potent and competitive eIF4E/eIF4G interaction inhibitor which binds to eIF4E with KD of 25 μM. 4EGI-1 has been shown to amplify TRAIL (tumor necrosis factor-related apop...
    Catalog No: V2815
    CAS No. (CAS Registry Number): 865783-99-9
    Description: Briciclib (also known as ON 013105; ON 014185) is an orally bioavailable small molecule and a disodium phosphate ester prodrug of ON 013100 with improved water solubility compared to ON 0...
    Catalog No: V11588
    CAS No. (CAS Registry Number): 2143542-28-1
    Description: 2BAct is a novel, potent, highly selective, CNS-permeable, and orally bioactive eif2b (eukaryotic initiation factor 2B) activator with an EC50 of 33 nM, it prevents neurological defe...
    Catalog No: V41046
    CAS No. (CAS Registry Number): 548470-11-7
    Description: ISRIB (mixed cis- and trans-isomer) is a novel and potent ISR (Integrated Stress Response) Inhibitor. It acts the downstream of PERK signaling pathway, targeting interactions between...
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