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    Catalog No: V1588
    CAS No. (CAS Registry Number): 955365-80-7
    Description: Adavosertib (also known as AZD-1775 and MK-1775) is a novel potent and selective small molecule Wee1 tyrosine kinase inhibitor with IC50 of 5.2 nM in a cell-free assay; it hinders G2...
    Catalog No: V2724
    CAS No. (CAS Registry Number): 413611-93-5
    Description: 10074-G5 is a potent inhibitor of c-Myc-Max dimerization and interaction with an IC50 of 146 μM and with anticancer activities. 10074-G5 binds to and distorts the bHLH-ZIP domain of ...
    Catalog No: V2729
    CAS No. (CAS Registry Number): 1338806-73-7
    Description: CFI400945 is a potent, selective, and orally bioavailable PLK4 (polo-like kinase 4) inhibitor with IC50 value of 2.8 ±1.4 nM and potential antineoplastic activity. CFI-400945 se...
    Catalog No: V2731
    CAS No. (CAS Registry Number): 1453834-21-3
    Description: LDC4297 is a novel and potent CDK7 (Cyclin-dependent protein kinase 7) inhibitor with IC50 of 0.13±0.06 nM for CDK7 and IC50s between 10 nM and 10,000 nM for all other anal...
    Catalog No: V2732
    CAS No. (CAS Registry Number): 1489389-18-5
    Description: CCT245737 is a novel, potent, orally available and selective ATP-competitive inhibitor of CHK1 (checkpoint kinase 1) with an IC50 of 30-220 nM. It shows5000-fold over these enzymes.&...
    Catalog No: V2742
    CAS No. (CAS Registry Number): 1883423-59-3
    Description: MSC2530818 is novel,  potent, selective and orally available small molecule inhibitor of cyclin dependent kinase CDK8 with the IC50 of 2.6 nM. It demonstrates exc...
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