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    Catalog No: V1689
    CAS No. (CAS Registry Number): 873054-44-5
    Description: Ivacaftor (also known as VX-770; trade name: KALYDECO and Symdeko) is a potent and orally bioactive potentiator of CFTR (cystic fibrosis transmembrane conductance regulator) tar...
    Catalog No: V1690
    CAS No. (CAS Registry Number): 936727-05-8
    Description: Lumacaftor (also known as VX-809 or VRT 826809) is a potent and orally active CFTR corrector that acts to correct CFTR mutations common in cystic fibrosis by increasing mutant C...
    Catalog No: V1691
    CAS No. (CAS Registry Number): 1152311-62-0
    Description: Tezacaftor (formerly VX-661; trade name: Symdeko) is a second F508del CFTR corrector that is able to help CFTR protein reach the cell surface. VX-661 is potentially useful for t...
    Catalog No: V1692
    CAS No. (CAS Registry Number): 136790-76-6
    Description: Lubiprostone (also known as SPI-0211; RU-0211), a potent activator of ClC-2 chloride channels, is a medication used in the management of idiopathic chronic constipation. It was ...
    Catalog No: V1693
    CAS No. (CAS Registry Number): 307510-92-5
    Description: CFTRinh-172 (also known as CFTR inhibitor 172) is a potent, voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or...
    Catalog No: V1694
    CAS No. (CAS Registry Number): 1191252-49-9
    Description: IOWH-032 is a potent and synthetic CFTR inhibitor with IC50 of 1.01 μM in CHO-CFTR cell based assays. IOWH032 inhibited CFTR activity with IC50 value of 6.87 μM in T84-CFTR cell base...
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