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    Catalog No: V1687
    CAS No. (CAS Registry Number): 659730-32-2
    Description: AMG 517 is a novel, potent and selective TRPV1 (vanilloid receptor-1) antagonist which antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM...
    Catalog No: V1688
    CAS No. (CAS Registry Number): 775304-57-9
    Description: Ataluren (also known as PTC124) is a novel, potent and orally bioavailable CFTR-G542X nonsense allele inhibitor that selectively induces ribosomal read-through of premature but ...
    Catalog No: V1689
    CAS No. (CAS Registry Number): 873054-44-5
    Description: Ivacaftor (also known as VX-770; trade name: KALYDECO and Symdeko) is a potent and orally bioactive potentiator of CFTR (cystic fibrosis transmembrane conductance regulator) tar...
    Catalog No: V1690
    CAS No. (CAS Registry Number): 936727-05-8
    Description: Lumacaftor (also known as VX-809 or VRT 826809) is a potent and orally active CFTR corrector that acts to correct CFTR mutations common in cystic fibrosis by increasing mutant C...
    Catalog No: V1691
    CAS No. (CAS Registry Number): 1152311-62-0
    Description: Tezacaftor (formerly VX-661; trade name: Symdeko) is a second F508del CFTR corrector that is able to help CFTR protein reach the cell surface. VX-661 is potentially useful for t...
    Catalog No: V1692
    CAS No. (CAS Registry Number): 136790-76-6
    Description: Lubiprostone (also known as SPI-0211; RU-0211), a potent activator of ClC-2 chloride channels, is a medication used in the management of idiopathic chronic constipation. It was ...
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