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    Catalog No: V1559
    CAS No. (CAS Registry Number): 741713-40-6
    Description: R547 (Ro 4584820) is a potent, selective and ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kina...
    Catalog No: V2731
    CAS No. (CAS Registry Number): 1453834-21-3
    Description: LDC4297 is a novel and potent CDK7 (Cyclin-dependent protein kinase 7) inhibitor with IC50 of 0.13±0.06 nM for CDK7 and IC50s between 10 nM and 10,000 nM for all other anal...
    Catalog No: V2742
    CAS No. (CAS Registry Number): 1883423-59-3
    Description: MSC2530818 is novel,  potent, selective and orally available small molecule inhibitor of cyclin dependent kinase CDK8 with the IC50 of 2.6 nM. It demonstrates exc...
    Catalog No: V2743
    CAS No. (CAS Registry Number): 1366002-50-7
    Description: Senexin A is a novel, potent, selective and ATP site competitive inhibitor of CDK8 and CDK19 with Kd values of 0.83 μM and 0.31 μM for CDK8 and CDK19, respectively....
    Catalog No: V2744
    CAS No. (CAS Registry Number): 1234015-52-1 (free base)
    Description: Prexasertib (also known as LY2606368) is a novel, potent, selective and ATP competitive inhibitor of the CHK1 (checkpoint kinase 1) protein kinase with IC50&...
    Catalog No: V2745
    CAS No. (CAS Registry Number): 1629268-00-3
    Description: ARS-853 is a  novel, potent, selective, and covalent inhibitor of KRAS(G12C) with IC50 of 2.5 μM. It inhibits mutant KRAS-driven signaling by binding to the ...
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