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    Catalog No: V0643
    CAS No. (CAS Registry Number): 936563-96-1
    Description: Ibrutinib (PCI-32765; Imbruvica) is a covalent/irreversible and orally bioavailable Brutons tyrosine kinase (Btk) inhibitor with IC50 of 0.5 nM in cell-free assays, it is modest...
    Catalog No: V0644
    CAS No. (CAS Registry Number): 1202757-89-8
    Description: Spebrutinib (formerly also known as AVL-292 or CC-292) is a novel, potent, covalent, orally bioactive, and highly selective BTK inhibitor with IC50 ofReferences: J Pharmacol Exp...
    Catalog No: V0645
    CAS No. (CAS Registry Number): 1202759-32-7
    Description: CNX-774 is a nove, potent, irreversible/covalent, orally bioactive, and highly selective BTK (Bruton’s tyrosine kinase) inhibitor with IC50 ofReferences: 17th North Am Meet Int Soc S...
    Catalog No: V0646
    CAS No. (CAS Registry Number): 910232-84-7
    Description: CGI1746 is a novel, potent and highly selective small-molecule inhibitor of the Btk with IC50 of 1.9 nM. CGI-1746 potently inhibits both auto- and transphosphorylation of BTK. IT has ...
    Catalog No: V0647
    CAS No. (CAS Registry Number): 244240-24-2
    Description: LFM-A13 is a novel, potent and specific Bruton's tyrosine kinase (BTK) inhibitor with IC50 of 2.5 μM, 100-fold selectivity over other protein kinases including JAK1, JAK2, HCK, EGFR,a...
    Catalog No: V0648
    CAS No. (CAS Registry Number): 1242156-23-5
    Description: RN486 (RN-486) is a novel, potent and selective BTK (Bruton's tyrosine kinase) inhibitor with IC50 of 4 nM. RN486 not only potently and selectively inhibited the Btk enzyme, but also ...
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