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    Catalog No: V0015
    CAS No. (CAS Registry Number): 213261-59-7
    Description: RITA (also known as NSC-652287) is a novel and potent inhibitor of p53-HDM-2 protein-protein interaction with potential anticancer activity. It binds to p53dN with a Kd of 1.5 nM, an...
    Catalog No: V0016
    CAS No. (CAS Registry Number): 380315-80-0
    Description: Tenovin-1, a small molecule compound discovered by a cell-based screen, is a novel and potent activator of p53 that protects against MDM2-mediated p53 degradation. It acts by inhibit...
    Catalog No: V0017
    CAS No. (CAS Registry Number): 71555-25-4
    Description: NSC319726 is a novel and potent p53(R175) mutant reactivator with with potential anticancer activity. It exhibits growth inhibition in cells expressing mutant p53 (IC50 of 8 nM ...
    Catalog No: V0018
    CAS No. (CAS Registry Number): 803647-40-7
    Description: NSC59984 is a novel and potent activator of p53 with potential anticancer activity. It acts via induction of mutant p53 protein degradation and p73 activation. References: ...
    Catalog No: V0020
    CAS No. (CAS Registry Number): 64984-31-2
    Description: Pifithrin-μ (NSC303580) is a novel and potent inhibitor of p53 binding and p53-mediated apoptosis with a Kd of 0.82 mM in vitro. It has antitumor and neuroprotective activity. R...
    Catalog No: V0021
    CAS No. (CAS Registry Number): 1303607-60-4
    Description: MI-773 (2'S,3R isomer, SAR405838) is a novel, potent, specific and orally bioavailable small molecule antagonist of MDM2/piro-oxindole HDM2 (Murine double minute 2/human double m...
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