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    Catalog No: V0007
    CAS No. (CAS Registry Number): 65673-63-4
    Description: HA14-1 is a novel, potent and non-peptidic inhibitor of a B-cell lymphoma 2 (Bcl-2) surface pocket with IC50 of ~9 μM. HA14-1 binds to Bcl-2 by mimicking the BH3 domain required for ...
    Catalog No: V0008
    CAS No. (CAS Registry Number): 1228108-65-3
    Description: Sabutoclax (BI-97C1), a derivative of apogossypolone, is a novel and potent pan-Bcl-2 inhibitor with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM for Bcl-xL, Bcl-2, Mcl-1 ...
    Catalog No: V0009
    CAS No. (CAS Registry Number): 518303-20-3
    Description: UMI-77 (UMI 77; UMI77) is a novel, potent and selective Mcl-1 (Myeloid cell leukemia-1) inhibitor with Ki of 490 nM. Myeloid cell leukemia-1 (Mcl-1) is a member of the prosurvival Bc...
    Catalog No: V0010
    CAS No. (CAS Registry Number): 1668553-26-1
    Description: A-1210477 is a novel, potent and specific MCL-1 (Myeloid cell leukemia-1) inhibitor with Ki and IC50 of 0.45 nM and 26.2 nM, respectively. In MCL-1-dependent SVEC cells, tr...
    Catalog No: V0013
    CAS No. (CAS Registry Number): 881202-45-5
    Description: Serdemetan (formerly JNJ26854165; JNJ-26854165; JNJ 26854165), originally developed as an activator of p53, is now considered to be a novel, potent and orally bioactive antagonist of...
    Catalog No: V0014
    CAS No. (CAS Registry Number): 63208-82-2
    Description: Pifithrin-α ((PFTα) is a novel and potent inhibitor of p53, acting by inhibiting p53 protein transcription and p53-dependent transactivation of p53-responsive genes. It also act...
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