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Amino Acids
Signaling Pathways
Apoptosis
♦
Bcl-2
(
19
)
♦
p53
(
12
)
♦
Caspase
(
17
)
♦
TNFa
(
16
)
♦
Mdm2
(
17
)
♦
c-RET
(
4
)
♦
IAP
(
7
)
♦
PERK
(
4
)
♦
PD-1/PD-L1
(
15
)
♦
Survivin
(
1
)
♦
Apoptosis
(
27
)
♦
RIP kinase
(
7
)
♦
ROS
(
1
)
♦
Cytohesin
(
1
)
♦
Ras
(
1
)
♦
Thymidylate Synthase
(
3
)
♦
DAPK
(
1
)
♦
Ferroptosis
(
1
)
♦
ASK
(
1
)
♦
FKBP
(
1
)
♦
Ferroptosis
(
1
)
PI3K/Akt/mTOR
♦
PI3K
(
72
)
♦
Akt
(
26
)
♦
mTOR
(
25
)
♦
GSK-3
(
18
)
♦
ATM/ATR
(
0
)
♦
PDK-1
(
4
)
♦
S6 kinase
(
6
)
♦
AMPK
(
14
)
♦
DNA-PK
(
5
)
♦
PTEN
(
1
)
♦
PDPK1
(
1
)
♦
NUDIX
(
1
)
♦
PDHK
(
1
)
♦
PI4K
(
1
)
♦
PP2A
(
1
)
Epigenetics
♦
HDAC
(
6
)
♦
HIF
(
7
)
♦
PARP
(
0
)
♦
JAK
(
40
)
♦
Aurora Kinase
(
23
)
♦
Histone Acetyltransferase
(
9
)
♦
Histone Demethylase
(
15
)
♦
Histone Methyltransferase
(
46
)
♦
DNA Methyltransferase
(
9
)
♦
Epigenetic Reader Domain
(
30
)
♦
Sirtuin
(
13
)
♦
Pim
(
6
)
♦
PKC
(
8
)
♦
SMYD
(
1
)
♦
Methionine Adenosyltransferase
(
1
)
♦
MicroRNA
(
2
)
♦
AMPK
(
1
)
♦
Protein Arginine Deiminase
(
2
)
MAPK
♦
MEK
(
19
)
♦
ERK
(
16
)
♦
Raf
(
18
)
♦
JNK
(
15
)
♦
p38 MAPK
(
20
)
♦
RSK
(
3
)
♦
Mixed Lineage Kinase
(
1
)
♦
KLF
(
1
)
♦
MNK
(
2
)
Protein Tyrosine Kinase
♦
VEGFR
(
58
)
♦
EGFR
(
49
)
♦
PDGFR
(
17
)
♦
c-MET
(
19
)
♦
HER-2
(
2
)
♦
ALK
(
16
)
♦
FLT3
(
11
)
♦
FGFR
(
15
)
♦
IFG-1R
(
10
)
♦
c-Kit
(
6
)
♦
Tie-2
(
1
)
♦
CSF-1R
(
3
)
♦
TAM Receptor
(
7
)
♦
Trk receptor
(
4
)
♦
c-RET
(
0
)
♦
Axl
(
1
)
♦
Bcr-Abl
(
4
)
♦
Ephrin Receptor
(
1
)
♦
Pyk2
(
1
)
♦
c-Fms
(
4
)
♦
DDR
(
1
)
♦
FLT3
(
0
)
♦
HER2
(
1
)
♦
Src
(
2
)
♦
Syk
(
1
)
♦
DYRK
(
3
)
♦
FAK
(
1
)
Angiogenesis
♦
VEGFR
(
1
)
♦
EGFR
(
1
)
♦
PDGFR
(
0
)
♦
HIF
(
3
)
♦
HER-2
(
0
)
♦
JAK
(
0
)
♦
FLT3
(
0
)
♦
FGFR
(
0
)
♦
BTK
(
10
)
♦
Syk
(
6
)
♦
FAK
(
8
)
♦
Src
(
8
)
♦
Bcr-Abl
(
10
)
♦
VDA
(
3
)
♦
ALK
(
1
)
Proteases
♦
Proteasome
(
13
)
♦
Cysteine Protease
(
12
)
♦
Serine Protease
(
6
)
♦
Gamma-secretase
(
10
)
♦
HCV Protease
(
5
)
♦
HIV Protease
(
7
)
♦
MMP
(
7
)
♦
DPP-4
(
9
)
♦
Caspase
(
0
)
♦
Acyltransferase
(
1
)
♦
Tyrosinase
(
1
)
♦
Glutaminase
(
2
)
♦
Thrombin
(
3
)
♦
3C-Like Protease
(
1
)
NF-kB
♦
NOD1
(
2
)
♦
IκB/IKK
(
20
)
♦
NF-κB
(
37
)
♦
HDAC
(
0
)
♦
ROS
(
1
)
Autophagy
♦
Autophagy
(
34
)
♦
LRRK2
(
6
)
♦
ULK
(
2
)
♦
Mitophagy
(
1
)
JAK/STAT
♦
JAK
(
2
)
♦
STAT
(
5
)
♦
EGFR
(
11
)
♦
Pim
(
4
)
Metabolism
♦
PDE
(
28
)
♦
P450 (e.g. CYP)
(
27
)
♦
PPAR
(
18
)
♦
Phospholipase
(
8
)
♦
DHFR
(
6
)
♦
Dehydrogenase
(
24
)
♦
HSP
(
20
)
♦
Carbonic Anhydrase
(
16
)
♦
MAO
(
2
)
♦
FAAH
(
6
)
♦
CETP
(
4
)
♦
Transferase
(
10
)
♦
HMG-CoA Reductase
(
11
)
♦
Hydroxylase
(
8
)
♦
IDO
(
7
)
♦
Retinoid Receptor
(
8
)
♦
Factor Xa
(
5
)
♦
AhR
(
3
)
♦
Ferroptosis
(
3
)
♦
Casein Kinase
(
7
)
♦
NAMPT
(
3
)
♦
Glucosylceramide Synthase
(
2
)
♦
Aldose Reductase
(
1
)
♦
ATP-citrate lyase
(
1
)
♦
Carbohydrate Metabolism
(
1
)
♦
FXR
(
5
)
♦
IAP
(
1
)
♦
Lipoxygenase
(
5
)
♦
Mitochondrial Metabolism
(
1
)
♦
PCSK9
(
2
)
♦
Phosphorylase
(
1
)
♦
Serine hydrolase
(
1
)
♦
SGK
(
1
)
♦
SCD
(
1
)
♦
Vitamin
(
9
)
♦
Acyltransferase
(
2
)
♦
CAR
(
2
)
♦
ROR
(
3
)
♦
PRMT
(
1
)
♦
PGC-1α
(
1
)
♦
Lipase
(
1
)
♦
OXPHOS
(
2
)
♦
Peroxidases
(
2
)
♦
Phosphatase
(
2
)
♦
Decarboxylase
(
3
)
♦
Prostaglandin Receptor
(
1
)
♦
Serine/threonin kinase
(
2
)
♦
Fatty Acid Synthase
(
3
)
♦
THR
(
2
)
♦
Glutathione
(
1
)
♦
CPT
(
1
)
♦
Acetyl-CoA Carboxylase
(
1
)
♦
AChR
(
1
)
♦
cGAS
(
1
)
Neuronal Signaling
♦
5-HT Receptor
(
3
)
♦
COX
(
41
)
♦
GluR
(
20
)
♦
Adrenergic Receptor
(
11
)
♦
AChR Receptor
(
62
)
♦
Histamine Receptor
(
4
)
♦
Dopamine Receptor
(
8
)
♦
Opioid Receptor
(
3
)
♦
GABA Receptor
(
14
)
♦
P-gp
(
0
)
♦
CaMK
(
10
)
♦
P2 Receptor
(
8
)
♦
OX Receptor
(
1
)
♦
MT Receptor
(
0
)
♦
BACE
(
2
)
♦
Gamma-secretase
(
0
)
♦
Beta Amyloid
(
13
)
♦
Monoamine Oxidase
(
5
)
♦
P2Y Receptor
(
1
)
♦
NMDAR
(
3
)
♦
γ-secretase
(
1
)
♦
Calcium Channel
(
3
)
♦
Serotonin Transporter
(
4
)
♦
Transthyretin (TTR)
(
1
)
♦
Notch
(
4
)
♦
ChE
(
6
)
♦
BChE
(
1
)
♦
Glucosylceramide Synthase
(
1
)
♦
AAK1
(
1
)
♦
Dopamine Transporter
(
2
)
♦
Sigma Receptor
(
2
)
♦
Tau Protein
(
1
)
Ubiquitin
♦
E2 conjugating
(
2
)
♦
p97
(
3
)
♦
E3 Ligase
(
2
)
♦
DUB
(
13
)
♦
Proteasome
(
0
)
♦
E1 Activating
(
2
)
Stem Cells/Wnt
♦
Hedgehog/Smoothened ROCK
(
2
)
♦
ROCK
(
0
)
♦
Wnt/beta-catenin
(
13
)
♦
Gamma-secretase
(
0
)
♦
Casein Kinase
(
3
)
♦
TGF–beta/Smad
(
1
)
♦
STAT
(
9
)
♦
JAK
(
0
)
♦
GSK-3
(
1
)
♦
Smo
(
2
)
♦
PKA
(
1
)
♦
Oct
(
2
)
♦
Porcupine
(
1
)
♦
Hippo (MST)
(
1
)
DNA Damage
♦
Telomerase
(
3
)
♦
Topoisomerase
(
47
)
♦
DNA/RNA Synthesis
(
84
)
♦
HDAC
(
41
)
♦
ATM/ATR
(
14
)
♦
PARP
(
34
)
♦
Sirtuin
(
1
)
♦
DNA Stain
(
3
)
♦
Nucleoside Antimetabolite/Analog
(
2
)
♦
DNA alkylator
(
4
)
♦
p97
(
1
)
♦
CRISPR/Cas9
(
1
)
♦
SMN
(
1
)
♦
HSP
(
3
)
♦
RNR
(
2
)
♦
OGG1
(
1
)
♦
RAD51
(
1
)
GPCR & G Protein
♦
cAMP
(
3
)
♦
Adenosine Receptor
(
24
)
♦
Vasopressin Receptor
(
7
)
♦
CXCR
(
13
)
♦
CaSR
(
4
)
♦
PAFR
(
2
)
♦
CGRP Receptor
(
1
)
♦
LPA Receptor
(
2
)
♦
SGLT
(
6
)
♦
S1P Receptor
(
11
)
♦
Endothelin Receptor
(
10
)
♦
Cannabinoid Receptor
(
13
)
♦
5-HT Receptor
(
101
)
♦
Adrenergic Receptor
(
83
)
♦
Histamine Receptor
(
57
)
♦
Dopamine Receptor
(
59
)
♦
Opioid Receptor
(
17
)
♦
Hedgehog/Smoothened ROCK
(
11
)
♦
OX Receptor
(
8
)
♦
MT Receptor
(
2
)
♦
Guanylate Cyclase
(
6
)
♦
LPL Receptor
(
10
)
♦
NPY receptor
(
1
)
♦
Angiotensin Receptor
(
10
)
♦
Free Fatty Acid Receptor
(
4
)
♦
GnRH Receptor
(
4
)
♦
GPR
(
14
)
♦
Leukotriene Receptor
(
2
)
♦
mAChR
(
16
)
♦
Neurotensin Receptor
(
1
)
♦
Prostaglandin Receptor
(
11
)
♦
Sigma Receptor
(
1
)
♦
PAR
(
4
)
♦
CCR
(
2
)
♦
GCGR
(
8
)
♦
GHSR
(
2
)
♦
GPCR19
(
2
)
♦
LTR
(
1
)
♦
mGluR
(
10
)
♦
PKD
(
1
)
♦
Ras
(
4
)
♦
CCK receptor
(
4
)
♦
Melatonin Receptor
(
2
)
♦
Formyl Peptide Receptor
(
1
)
♦
G protein-coupled Bile Acid Receptor
(
1
)
♦
Melanocortin Receptor
(
3
)
♦
Neurokinin Receptor
(
2
)
♦
Oxytocin Receptor
(
1
)
♦
Somatostatin Receptor
(
2
)
♦
Adenylate Cyclase
(
2
)
♦
Bradykinin Receptor
(
2
)
♦
P2Y Receptor
(
1
)
♦
Urotensin Receptor
(
1
)
♦
TSH Receptor
(
1
)
♦
PKG
(
1
)
TGF-beta/Smad
♦
MT Receptor
(
20
)
♦
Bcr-Abl
(
0
)
♦
ROCK
(
20
)
♦
PKC
(
11
)
♦
TGF-β Receptor
(
7
)
Cell Cycle
♦
CDK
(
55
)
♦
Rho
(
17
)
♦
PLK
(
14
)
♦
Chk
(
8
)
♦
Aurora Kinase
(
0
)
♦
ROCK
(
4
)
♦
PD-1/PD-L1
(
0
)
♦
c-Myc
(
4
)
♦
Wee1
(
1
)
♦
APC
(
2
)
♦
HSP
(
3
)
♦
Microtubule/Tubulin
(
22
)
♦
HDAC
(
5
)
♦
PPAR
(
8
)
♦
Eukaryotic Initiation Factor
(
1
)
♦
Topoisomerase
(
4
)
♦
Ras
(
2
)
♦
Mps1
(
1
)
♦
Kinesin
(
3
)
♦
PAK
(
3
)
♦
PERK
(
1
)
♦
Antifolate
(
2
)
♦
TOPK
(
1
)
♦
PARP
(
1
)
♦
LIMK
(
1
)
♦
G-quadruplex
(
1
)
Cytoskeletal Signaling
♦
Bcr-Abl
(
1
)
♦
Wnt/beta-catenin
(
10
)
♦
PKC
(
0
)
♦
FAK
(
0
)
♦
HSP
(
1
)
♦
Dynamin
(
3
)
♦
PAK
(
4
)
♦
Integrin
(
16
)
♦
Microtubule Associated
(
25
)
♦
Kinesin
(
6
)
♦
MLCK
(
1
)
♦
Gap Junction Protein
(
3
)
♦
Myosin
(
2
)
Transmembrane
♦
P-gp
(
9
)
♦
Proton Pump
(
16
)
♦
GABA Receptor
(
23
)
♦
Sodium Channel
(
43
)
♦
Potassium Channel
(
40
)
♦
Calcium Channel
(
56
)
♦
ATPase
(
10
)
♦
CRM1
(
2
)
♦
TRPV
(
0
)
♦
CFTR
(
2
)
♦
OCT
(
0
)
♦
Amino Acid Transporter
(
1
)
♦
Monocarboxylate Transporter
(
0
)
♦
Apical Sodium-Dependent Bile Acid Transporter
(
1
)
♦
Chloride Channel
(
3
)
♦
GlyT
(
2
)
♦
P2 Receptor
(
2
)
♦
TRP Channel
(
19
)
♦
BCRP
(
2
)
♦
CD markers
(
2
)
♦
HCN Channel
(
3
)
♦
iGluR
(
12
)
♦
Interleukins
(
1
)
♦
nAChR
(
6
)
♦
OAT
(
1
)
♦
SGLT
(
2
)
♦
Monocarboxylate Transporter
(
1
)
♦
Adrenergic Receptor
(
1
)
♦
P2X Receptor
(
1
)
♦
CRAC Channel
(
2
)
♦
Monoamine Transporter
(
2
)
♦
Piezo Channel
(
1
)
♦
Aquaporin
(
1
)
♦
EAAT
(
1
)
Endocrinology & Hormones
♦
Opioid Receptor
(
0
)
♦
Glucocorticoid Receptor
(
8
)
♦
Estrogen/progestogen Receptor
(
47
)
♦
Androgen Receptor
(
18
)
♦
RAAS
(
27
)
♦
Aromatase
(
6
)
♦
GPR
(
8
)
♦
5-alpha Reductase
(
2
)
♦
Adrenergic Receptor
(
1
)
♦
Mineralocorticoid Receptor
(
2
)
♦
ACE
(
3
)
♦
TSH Receptor
(
2
)
♦
THR
(
1
)
Microbiology
♦
HCV Protease
(
1
)
♦
HIV Protease
(
2
)
♦
CCR
(
2
)
♦
Reverse Transcriptase
(
31
)
♦
Integrase
(
0
)
♦
Bacterial
(
12
)
♦
Anti-infection
(
4
)
♦
HSV
(
1
)
♦
Influenza Virus
(
1
)
♦
RSV
(
1
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3
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6
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7
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432
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332
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7
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9
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4
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13
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4
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16
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2
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8
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6
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2
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3
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2
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2
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3
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5
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7
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1
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15
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5
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3
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8
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PROTAC
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PROTAC Linkers
(
40
)
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E3 Ligase Ligand-Linker Conjugates
(
8
)
Unfolded Protein Response
♦
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1
)
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IRE1
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2
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1
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1
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443
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1969
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384
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Fine Intermediates/Building Blocks
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Bulletin Board
Bis-Boc-thiourea
Catalog No：
V37134
CAS No. (CAS Registry Number)：
145013-05-4
Price：
$0/g
Description: Bis-Boc-thiourea is an amino acid.
DSC
Catalog No：
V37135
CAS No. (CAS Registry Number)：
74124-79-1
Price：
$0/g
Description: DSC is an amino acid.
HMP-Linker
Catalog No：
V37136
CAS No. (CAS Registry Number)：
68858-21-9
Price：
$0/g
Description: HMP-Linker is an amino acid.
H-b-Ala-OEt.HCl
Catalog No：
V37137
CAS No. (CAS Registry Number)：
4244-84-2
Price：
$0/g
Description: H-b-Ala-OEt.HCl is an amino acid.
H-Ala-Obzl.HCl
Catalog No：
V37138
CAS No. (CAS Registry Number)：
5557-83-5
Price：
$0/g
Description: H-Ala-Obzl.HCl is an amino acid.
H-Ala-OtBu.HCl
Catalog No：
V37139
CAS No. (CAS Registry Number)：
13404-22-3
Price：
$0/g
Description: H-Ala-OtBu.HCl is an amino acid.
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