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    Catalog No: V0075
    CAS No. (CAS Registry Number): 2089288-03-7
    Description: AZD1390 is a novel, potent, selective, first-in-class orally bioavailable and CNS penetrant ATM inhibitor with an IC50 of 0.78 nM in cell assays. It is 10,000-fold more sel...
    Catalog No: V0181
    CAS No. (CAS Registry Number): 1542705-92-9
    Description: CB-5083 is a novel, potent, selective, first in class and orally bioavailable p97 AAA ATPase inhibitor with IC50 of 11 nM. CB-5083 disrupts cellular protein homeostasis and demonstrates a...
    Catalog No: V0196
    CAS No. (CAS Registry Number): 1223001-51-1
    Description: Torin 2 is a novel, potent and selective ATP-competitive mTOR inhibitor with IC50 of 0.25 nM in p53−/− MEFs cell line; it demonstrated 800-fold greater selectivity for mTOR than PI3K...
    Catalog No: V0204
    CAS No. (CAS Registry Number): 1345675-02-6
    Description: ETP-46464 is a novel, potent and selective inhibitor of ATR (Ataxia-telangiectasia mutated) with IC50 of 25 nM. It is also an effective mTOR with IC50s of 0.6 nM....
    Catalog No: V0230
    CAS No. (CAS Registry Number): 905973-89-9
    Description: CGK 733 is a novel, potent and selective inhibitor of ATM and ATR with IC50 of ~200 nM. CGK733 significantly enhanced taxol-induced cytotoxicity in HBV-positive HepG2.2.15 cells. The mech...
    Catalog No: V0231
    CAS No. (CAS Registry Number): 1233339-22-4
    Description: AZ20 is a novel potent and selective inhibitor of ATR protein kinase with IC50 of 5 nM in a cell-free assay, it showed 8-fold selectivity over mTOR. ATR is an attractive new anticancer dr...
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