Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The sense strand is broken down as the short dsRNA unwinds. With various protein components, the antisense strand forms the RNA-induced silencing complex (RISC). The target gene's mRNA is specifically complementary to the antisense strand that RISC retains. The target gene's mRNA can be cut and degraded by the nuclease activity of RISC, which can also stop the target gene from being expressed. Inhibition of mRNA translation is the result of incomplete complementarity.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V79284 | Elebsiran sodium (VIR-2218 sodium) | Elebsiran sodium is an siRNA against HBV (hepatitis B virus) and hepatitis D virus (HDV) infection. | |
|
V103996 | FAK siRNA-1 | FAK siRNA-1 is a small interfering RNA (siRNA) targeting FAK, which has a knockdown effect on FAK. | |
|
V103997 | FAK siRNA-2 | FAK siRNA-2 is a small interfering RNA (siRNA) targeting FAK, which has a knockdown effect on FAK. | |
|
V103998 | FAKsiRNA-3 | FAKsiRNA-3 is a small interfering RNA targeting FAK messenger RNA. | |
|
|
V75253 | Fazirsiran (ARO-AAT) | 2175009-08-0 | Fazirsiran (ARO-AAT) is a second-generation RNA interference (RNAi) active molecule. |
|
|
V90312 | Fazirsiran sodium | 2175009-09-1 | Fazirsiran sodium is a second generation RNA interference (RNAi) active molecule. |
|
V73137 | Fitusiran (ALN-AT3SC; SAR439774) | 1499251-18-1 | Fitusiran (ALN-AT3SC) is a small interfering RNA that specifically targets antithrombin (AT) messenger RNA to reduce AT production in the liver. |
|
|
V116351 | FMN aptamer sodium | FMN aptamer sodium is a 77-nucleotide RNA aptamer that targets FMN (flavin mononucleotide). | |
|
|
V51385 | GalNAc unconjugated/naked Fitusiran | GalNAc unconjugated/naked Fitusiran is a small interfering RNA without conjugated GalNAc that specifically targets antithrombin (AT) messenger RNA to reduce AT production in the liver. | |
|
|
V87431 | GalNAc unconjugated/naked Fitusiran sodium | GalNAc unconjugated/naked Fitusiran (sodium) is a GalNAc-unconjugated small interfering RNA that specifically targets antithrombin (AT) messenger RNA to reduce AT production in the liver. | |
|
|
V51386 | GalNAc unconjugated/naked Inclisiran | GalNAc unconjugated/naked Inclisiran is a double-stranded small interfering RNA (siRNA) molecule without conjugated GalNAc that can inhibit the transcription of PCSK-9. | |
|
|
V110289 | GAPDH Positive Control siRNA (Human) | GAPDH positive control siRNA (human) is an siRNA product that can be used as a positive control for human GAPDH siRNA. | |
|
|
V110285 | GAPDH siRNA Positive Control (Mouse/Rat) | GAPDH siRNA positive control (mouse/rat) is an siRNA product that serves as a positive control for GAPDH siRNA in mice and rats. | |
|
|
V88923 | Givosiran sodium | Givosiran sodium is a small interfering RNA that targets the hepatic aminocellulose synthase 1 (ALAS1) messenger RNA. | |
|
V116909 | HA2 peptide | 117138-19-9 | HA2 peptide is a potent pH-responsive fusion peptide derived from hemagglutinin (HA). |
|
|
V116427 | HE4 aptamer sodium | Sodium HE4 aptamer is a DNA aptamer that can bind to HE4 (a biomarker for ovarian cancer). | |
|
V105343 | In vivo Jun Mouse Pre-designed siRNA-2 | In vivo Jun Mouse Pre-designed siRNA-2 is a siRNA product designed for the Jun (Mouse) gene and can be used for in vivo experiments in mice. | |
|
V105344 | In vivo Stat1 Mouse Pre-designed siRNA-1 | In vivo Stat1 Mouse Pre-designed siRNA-1 is a siRNA product designed for the Stat1 (mouse) gene and can be used for in vivo experiments in mice. | |
|
V105345 | In vivo Stat1 Mouse Pre-designed siRNA-2 | In vivo Stat1 Mouse Pre-designed siRNA-2 is a siRNA product designed for the Stat1 (mouse) gene and can be used for in vivo experiments in mice. | |
|
|
V83977 | Inclisiran sodium (ALN-PCSsc sodium) |
Products are for research use only; We do not sell to patients
Copyright 2020 InvivoChem LLC | All Rights Reserved
