Serine (Ser) proteases are enzymes that catalyze the hydrolysis of specific peptide bonds in their substrates, and one of the amino acids in the enzyme's active site is always a serine. The trypsin family and the subtilisin family are two families that have received particular attention in research. The process of blood clotting, protein digestion, cell signaling, inflammation, and protein processing are just a few of the numerous cellular and extracellular functions that serine proteases are essential for. A threonine residue is present in the active site of a family of proteolytic enzymes known as thronine (Thr) proteases. Although the catalytic subunits of the proteasome are the prototype members of this class of enzymes, the active site geometry and mechanism of acyltransferases were convergently evolved.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V73399 | Trypsin Inhibitor, soybean | 9035-81-8 | Trypsin Inhibitor, soybean is a potent and reversible inhibitor of trypsin. |
|
V71886 | UAMC-00050 | 2842774-51-8 | UAMC-00050 is a potent trypsin-like serine protease inhibitor. |
|
V71857 | Urokinase (peptidolytic) (Urokinase; Urokinase-type plasminogen activator; Uronase; Win 22005; Win-Kinase) | 9039-53-6 | Urokinase peptidolytic (Urokinase-type plasminogen activator) is a serine protease and an inactive form (zymogen) of the serine protease plasmin. |
|
V87720 | VD4162 | 2574390-19-3 | VD4162 (Compound 8b) is a macrocyclic inhibitor of serine proteases. |
|
V87721 | VD5123 | VD5123 is a serine protease inhibitor. | |
|
V70219 | Vevorisertib (ARQ 751) | 1416775-46-6 | Vevorisertib (ARQ 751) is an orally bioactive, potent and specific pan-AKT serine/threonine kinase inhibitor of AKT1 (IC50=0.55 nM), AKT2 (IC50=0.81 nM) and AKT3 (IC50= 1.31 nM) is inhibitory. |
|
V73408 | WNK1-IN-1 | 324022-39-1 | WNK1-IN-1 is a selective inhibitor of WNK1 with IC50 of 1.6 μM. |
|
V3433 | WNK463 | 2012607-27-9 | WNK463 (NVP-WNK463) is a novel, potent and orally bioavailable pan-WNK-kinase inhibitor withIC50s of 5, 1, 6, and 9 nM for WNK1, WNK 2, WNK 3, and WNK 4, respectively. |
|
V71880 | Z-Val-Gly-Arg-pNA | 78333-16-1 | Z-Val-Gly-Arg-pNA is a chromogenic substrate for urokinase. |
|
V73278 | ZK824859 hydrochloride | 2436760-76-6 | ZK824859 HCl is an orally bioactive and selective urokinase-type plasminogen activator (uPA) inhibitor for human uPA, tPA and plasmin with IC50 of 79 nM, 1580 nM and 1330 nM respectively. |
|
V71887 | α-Lytic protease (α-lytic protease; alphaLP) | 37288-76-9 | α-Lytic protease (alphaLP) is a serine endopeptidase. |
|
V51697 | Tilpisertib (GS-4875) | 2065153-41-3 | Tilpisertib (GS-4875) is a serine/threonine kinase inhibitor (WO2017007689). |
|
V87723 | Trypsin | 9002-07-7 | Recombinant Trypsin is a serine protease that hydrolyzes proteins at the carboxyl side of lysine or arginine. |
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