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Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. Endogenous variables like age, sex, body composition, genetics, and underlying pathologies have an impact on a given body fluid's metabolome. The activity of an enormous variety of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules typically keeps the levels of the enormous variety of unique small-molecule metabolites tightly regulated. In the brain, endogenous small molecules are typically present at levels that are tightly controlled.

Endogenous Metabolite related products

Structure Cat No. Product Name CAS No. Product Description
Prostaglandin D2-d4 (PGD2-d4) V74495 Prostaglandin D2-d4 (PGD2-d4) 211105-29-2 Prostaglandin D2-d4 is the deuterated form of Prostaglandin D2.
Prostaglandin D2-d9 (PGD2-d9) V72686 Prostaglandin D2-d9 (PGD2-d9) 2254642-52-7 Prostaglandin D2-d9 is the deuterated form of Prostaglandin D2.
Prostaglandin E2-d4 (PGE2-d4; Dinoprostone-d4) V74490 Prostaglandin E2-d4 (PGE2-d4; Dinoprostone-d4) 34210-10-1 Prostaglandin E2-d4 is the deuterated form of Prostaglandin E2.
Prostaglandin E2-d9 (PGE2-d9; Dinoprostone-d9) V74480 Prostaglandin E2-d9 (PGE2-d9; Dinoprostone-d9) 1356347-42-6 Prostaglandin E2-d9 is the deuterated form of Prostaglandin E2.
Prostaglandin F2α-1-glyceryl ester V102629 Prostaglandin F2α-1-glyceryl ester 43042-79-1 Prostaglandin F2 α-1-glyceride can be oxidized by 15-hydroxyprostaglandin dehydrogenase (15-HPGDH).
Prostaglandin I3 sodium V143240 Prostaglandin I3 sodium 68324-96-9 Prostaglandin I3 sodium is a platelet aggregation inhibitor with vasodilatory effects.
Prostaglandin J2 (prostaglandin J2; PGJ2) V72815 Prostaglandin J2 (prostaglandin J2; PGJ2) 60203-57-8 Prostaglandin J2 (PGJ2) is an endogenously produced metabolite of prostaglandin D2 (PGD2) and a potent PGD2 receptor (DP) agonist/activator with Ki of 0.9 nM and hCRTH2 for hDP and hCRTH2, respectively.
PROTAC IRAK3 degrade-1 V81932 PROTAC IRAK3 degrade-1 2712600-00-3 PROTAC IRAK3 degrade-1 (compound 23) is a potent and specific IRAK3 degrader (IC50 = 5 nM).
Protease for flavors V105865 Protease for flavors 37259-58-8 Flavoring protease is a biocatalyst and a key enzyme in new biocatalyst technology.
Protease, Rhizopus sp. V110181 Protease, Rhizopus sp. Proteases (Rhizopus) are enzymes that hydrolyze proteins by breaking down peptide bonds that link amino acids in polypeptide chains to initiate protein catabolism.
Protease, Streptomyces griseus V110168 Protease, Streptomyces griseus Streptomyces griseus proteases exhibit broad substrate specificity.
Protectin D1 (Neuroprotectin D1; NPD1) V72702 Protectin D1 (Neuroprotectin D1; NPD1) 660430-03-5 Protectin D1, neuroprotectin D1 produced by nerve cells, is a member of a new family of bioactive products produced from docosahexaenoic acid.
Protein A V92171 Protein A 308083-69-4 Protein A (SPA) is an immunoglobulin (Ig) binding protein present on the bacterial surface and freely secreted into the extracellular environment.
Protein Disulfide Isomerase, Human V119291 Protein Disulfide Isomerase, Human Human protein disulfide isomerases are oxidoreductases that are mainly found in the endoplasmic reticulum (ER).
Protein-arginine deiminase V70909 Protein-arginine deiminase 75536-80-0 Protein-arginine deiminase is a unique family of enzymes that catalyze the hydrolysis of peptidyl arginine to form peptidyl citrulline.
Proteinase, Aspergillus melleus V143429 Proteinase, Aspergillus melleus Proteinase, Aspergillus melleus, is a protein-degrading enzyme that initiates protein catabolism by hydrolyzing the peptide bonds that link amino acids in a polypeptide chain.
Protodioscin (Protodiosgenin) V72311 Protodioscin (Protodiosgenin) 55056-80-9 Protodioscin is the main steroidal saponin compound in fenugreek and has multiple effects like anti-lipidemia, anti-tumor, and cardiovascular protection.
Protoporphyrin IX disodium V93297 Protoporphyrin IX disodium 50865-01-5 Protoporphyrin IX disodium is the final intermediate in the heme biosynthetic pathway.
PRRSV/CD163-IN-1 V39839 PRRSV/CD163-IN-1 560995-89-3 PRRSV/CD163-IN-1 is a PRRSV/CD163 inhibitor.
Pseudane V V104771 Pseudane V 109072-26-6 Pseudomonas V is a secondary metabolite isolated from Pseudomonas M2.
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