Almost all living things contain potassium channels, which are the most common type of ion channel. They build pores across cell membranes that are selective for potassium. The majority of cell types contain potassium channels, which regulate a wide range of cellular activities. Potassium channels work to quickly and selectively conduct potassium ions down their electrochemical gradient. In many cells, these channels function to either set or reset the resting potential. The delayed counterflow of potassium ions in excitable cells, like neurons, shapes the action potential. Failure of potassium channels can lead to potentially fatal arrhythmias by helping to control the duration of the action potential in cardiac muscle. Maintaining vascular tone may also involve potassium channels.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V73595 | Cesium chloride | 7647-17-8 | Cesium chloride is a potassium channel inhibitor. |
|
V77154 | Charybdotoxin TFA | Charybdotoxin TFA is a 37-amino acid (AA) peptide that is a K+ channel blocker. | |
|
V73646 | Chlorahololide C | 1007859-25-7 | Chlorahololide C is a lindane sesquiterpene dimer extracted from Chloranthus holostegius. |
|
V73636 | Chlorahololide D | 943136-39-8 | Chlorahololide D is a potent and specific Potassium Channel blocker with IC50 of 2.7 μM. |
|
V73596 | Chromanol 293B | 163163-23-3 | Chromanol 293B selectively blocks slow delayed rectifier potassium currents (IKs) with IC50 of 1-10 μM and is a weak inhibitor of KATP channels. |
|
V73601 | Cibenzoline (Cifenline; Ro 22-7796) | 53267-01-9 | Cibenzoline is a potent KATP channel inhibitor that directly affects the pore-forming Kir6.2 subunit but not the SUR1 subunit. |
|
V101512 | Cibenzoline succinate | 100678-32-8 | Cifenline succinate is Cifenline succinate. |
|
V103447 | cis-KV1.3-IN-1 | 3052324-05-4 | cis-KV1.3-IN-1 (compound cis-18) is the cis isomer of KV1.3-IN-1. |
|
V114712 | CK-1649 chloride | 125883-03-6 | CK-1649 chloride is a class III antiarrhythmic drug. |
|
V73605 | Clamikalant sodium (HMR 1098) | 261717-22-0 | Clamikalant sodium (HMR 1098) is a non-selective and ATP-sensitive potassium (KATP) channel blocker. |
|
V131895 | CLE-030 | 2803111-66-0 | CLE-030 is a KCNQ2 agonist with non-gated current-regulating activity. |
|
V73631 | Clobutinol | 14860-49-2 | Clobutinol is a compound that has antitussive effects. |
|
V73584 | Clobutinol hydrochloride | 1215-83-4 | Clobutinol HCl Clobutinol is a compound with antitussive effects. |
|
V18559 | CLP-290 | 1181083-81-7 | CLP-290 is a novel and potent KCC2 modulator acting as a prodrug of CLP-257, and is highly selective for KCC2 over related Cl- transporters. |
|
V87214 | CPK20 | 2397708-22-2 | CPK20 is a potent and highly selective KCNT1 channel blocker and can be used in epilepsy research. |
|
V132140 | CPL500036 | 1829530-11-1 | CPL500036 is an orally effective, blood-brain barrier-crossing phosphodiesterase 10A (PDE10A) inhibitor with IC50 values of 1 nM (Reference 1) and 35 nM (Reference 2). |
|
V133164 | DABMA | 893603-33-3 | DABMA is a TMEM175 channel activator with an EC50 value of 17.9 μM for humans. |
|
V79006 | DAD | DAD is an ion channel blocker that blocks voltage-gated potassium channels and is a third-generation photoswitch that responds to visible light. | |
|
V78641 | DAD dichloride | DAD dichloride is an ion channel blocker (blocks voltage-gated potassium channels) and a third-generation photoswitch that responds to visible light. | |
|
V77108 | Dalazatide TFA (ShK-186 TFA) | Dalazatide (ShK-186) TFA is a specific peptide inhibitor of Kv1.3 potassium channel. |
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