Potassium Channel

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Potassium Channel

Almost all living things contain potassium channels, which are the most common type of ion channel. They build pores across cell membranes that are selective for potassium. The majority of cell types contain potassium channels, which regulate a wide range of cellular activities. Potassium channels work to quickly and selectively conduct potassium ions down their electrochemical gradient. In many cells, these channels function to either set or reset the resting potential. The delayed counterflow of potassium ions in excitable cells, like neurons, shapes the action potential. Failure of potassium channels can lead to potentially fatal arrhythmias by helping to control the duration of the action potential in cardiac muscle. Maintaining vascular tone may also involve potassium channels.

Potassium Channel related products

Cat No.	Product Name	CAS No.	Product Description
V2418	A2793	88349-90-0	A2793 inhibited TWIK-related acid-sensitive K+channel (TASK)-1 (100µM, 53.4% ± 13, 5%,n= 5).
V77708	Aa1 toxin		Aa1 toxin, a neurotoxic peptide obtained from the venom of Androctonus australis Garzoni, is a specific potassium channel blocker.
V77712	Aam-KTX		Aam-KTX is a Kv channel inhibitor (antagonist) with IC50s of 1.1 nM and >750 nM for Kv1.3 and Kv1.1, respectively.
V77827	ADWX 1		ADWX 1 is a novel peptide that potently targets Kv1.3, with IC50 of 1.89 pM.
V128350	ADWX 1 TFA		ADWX 1 TFA is a novel peptide inhibitor with high selectivity for the Kv1.3 channel and an IC50 value of 1.89 pM.
V94056	Aekatperone		Aekatperone is a reversible KATP channel inhibitor with IC50 of 9 μM.
V73643	Agitoxin-2	168147-41-9	Agitoxin-2 is a blocker of K+ channels, with IC50s of 201 pM and 144 pM for mKV1.3 and mKV1.1 respectively.
V77858	Agitoxin-2 TFA		Agitoxin-2 TFA is a K+ channel blocker with IC50s of 201 pM and 144 pM for mKV1.3 and mKV1.1 respectively.
V128427	AIC263282		AIC263282 is a potent hepatitis B virus (HBV) capsid assembly modulator with an EC50 value of 3.8 nM.
V116179	AL 0671	158513-06-5	AL 0671 is a potassium channel opener.
V4822	AM-92016 HCl	133229-11-5	AM-92016 HCl, the hydrochloride salt of AM-92016 (an oxypropanolamine analog of sotalol), is a novel, potent and specificIKinhibitor.
V77931	AmmTX3		AmmTX3 is a bioactive peptide toxin extracted from the venom of the scorpion Androctonus mauretanicus.
V77932	AmmTX3 TFA		AmmTX3 TFA is a bioactive peptide toxin extracted from the venom of the scorpion Androctonus mauretanicus.
V73615	Antiarrhythmic agent-1	136081-07-7	Antiarrhythmic agent-1 (Example I) is an antiarrhythmic agent and IKr potassium channel inhibitor (IC50<1 μM).
V87218	Antimalarial agent 41		Antimalarial agent 41 (Compound 17) has antimalarial activity and inhibits Plasmodium falciparum with IC50 of 40 nM (NF54 strain) and 76 nM (K1 strain).
V73607	AP14145 hydrochloride	2387505-59-9	AP14145 HCl is a potent NAM (negative allosteric modulator) of KCa2 (SK) channels with IC50 of 1.1 μM for both KCa2.2 (SK2) and KCa2.3 (SK3) channels.
V84179	AP30663
V77250	Apamin TFA (Apamin TFA)		Apamin TFA (Apamine TFA) is an 18-amino acid (AA) peptide neurotoxin found in melittin.
V73590	ASP2905	792184-90-8	ASP2905 is a potent and specific potassium channel Kv12.2 inhibitor encoded by the Kcnh3/BEC1 gene.
V11905	AUT1	1311136-84-1	AUT1 is a Kv3 potassium channel modulator which increases whole currents mediated by human Kv3.1b and Kv3.2a channels, with a concomitant leftward shift in the voltage-dependence of activation, while having a less potent effect on hKv3.3 currents.