A family of enzymes known as monoamine oxidases (MAO) catalyzes the oxidation of monoamines. In the majority of the body's cell types, they are discovered bound to the mitochondria's outer membrane. They are a member of the flavin-containing amine oxidoreductase protein family. The oxidative deamination of monoamines is catalyzed by monoamine oxidases. By using oxygen to remove an amine group from a molecule, the resulting aldehyde and ammonia are produced.Flavoproteins are monoamine oxidases because they have the cofactor FAD covalently bound to them. MAO dysfunction is thought to be the cause of a number of psychiatric and neurological disorders due to the critical part MAOs play in the inactivation of neurotransmitters. While MAO-B inhibitors are used alone or in combination to treat Alzheimer's and Parkinson's diseases, MAO-A inhibitors have antidepressant and antianxiety properties.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V34351 | Obtusin | 70588-05-5 | Isolated fromCassia obtusifoliaLinn seed, Obtusin is natural product of the triterpenoid class. |
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V3149 | Iproniazid | 54-92-2 | Iproniazid (brand/other names of Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, and irreversiblemonoamine oxidase inhibitor (MAOI). |
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V60115 | Osthenol | 484-14-0 | Osthenol (Ostenol) is a pre-acetylated coumarin extracted from the dry roots of Solanum solani. |
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V18542 | Clorgyline HCl (M&B 9302, MB9302) | 17780-75-5 | Clorgyline, formerly known as Clorgiline, M&B 9302 or MB9302, is a potent,irreversible and selective inhibitor of monoamine oxidase (MAO), it is structurally related to pargyline which is described as an antidepressant. |
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V5896 | Bifemelane HCl | 62232-46-6 | Bifemelane HCl (MCI-2016) is a potent, selective and competitive inhibitor of MAO (monoamine oxidase) A (MAO-A) with Ki of 4.20 μM. |
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V25757 | Mofegiline HCl | 120635-25-8 | Mofegiline HCl(MDL-72,974; MDL72,974), the hydrochloride salt ofMofegiline, is a potent andirreversibleinhibitor of monoamine oxidase B (MAO-B) and semicarbazide-sensitive amine oxidase (SSAO)with the potential to be used for the treatment for various diseases. |
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V24905 | Phenelzine Sulfate | 156-51-4 | Phenelzine sulfate is a non-selective and irreversible MAO (monoamine oxidase) inhibitor (MAOI) used as an antidepressant and anxiolytic (anti-anxiety). |
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V2308 | Lysyl oxidase inhbitor 1 | 2409963-83-1 | Lysyl oxidase inhbitor 1 is a novel and potent inhibitor of lysyl oxidase, whose upregulation by tumor cells may promote metastasis of the existing tumor, causing it to become malignant and cancerous. |
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V20851 | Hypericin (SGX301) | 548-04-9 | Hypericin(also known as SGX301), is a novel, first-in-class photodynamic therapy using a potent photosensitizer, synthetic hypericin, that is topically applied and activated by safe visible fluorescent light. |
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