Beta Amyloid

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Beta Amyloid

As the primary component of the amyloid plaques seen in the brains of Alzheimer patients, amyloid- (A) refers to peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease. The amyloid precursor protein (APP), which is cut by specific enzymes to produce A, produces the peptides. Amyloid molecules can group together to create a variety of flexible, soluble oligomers.A amyloid-peptide buildup results from excessive A production or malfunctioning clearance mechanisms. Amyloid- forms diffuse and neuritic plaques in the parenchyma and blood vessels by self-aggregating into oligomers of various sizes. Strong synaptotoxins, proteasome inhibition, mitochondrial inhibition, alteration of intracellular Ca2+ levels, and induction of inflammatory processes are all characteristics of amyloid-oligomers and plaques. Neuronal dysfunction is also thought to be influenced by the loss of A's typical physiological functions.

Beta Amyloid related products

Cat No.	Product Name	CAS No.	Product Description
V79406	hAChE/hBACE-1-IN-2		hAChE/hBACE-1-IN-2 is a potent, orally bioactive, BBB (blood-brain barrier) permeable (penetrable) triple inhibitor of hAChE/hBChE/hBACE-1 with IC50s of 0.113 μM, 1.48 μM and 0.38 μM respectively.
V71389	Heishuixiecaoline A	1469493-85-3	Heishuixiecaoline A is a sesquiterpenoid.
V71356	Hoechst 34580 tetrahydrochloride (HOE 34580 tetrahydrochloride)	2310135-08-9	Hoechst 34580 tetra HCl is a marking dye from the Hoechst range.
V116009	JBPOS-0101	1353949-71-9	JBPOS-0101 is a phenylcarbamate compound.
V97481	Kayaflavone	481-45-8	Kayafavone is an aminoflavonoid biflavonoid.
V138429	KHK6640		KHK6640 is a humanized anti-β-amyloid oligomer-specific antibody.
V96695	Lecanemab (Mouse IGG2a)		Lecanemab (Mouse IGG2a) is a monoclonal antibody targeting soluble β-amyloid protein with the potential to alleviate cognitive decline.
V16894	TRX-0237 mesylate	1236208-20-0	TRX-0237 mesylate (LMT-X; TRX0237;Leuco-MTx; LMTX; Hydromethylthionine mesylate), the mesylate salt ofTRX 0237 which is currentlyin phase III clinical trials by TauRx,is a 2nd-generation tau protein aggregation and TDP-43 aggregation inhibitor with the potential for the treatment of Alzheimers disease (AD) and frontotemporal dementia.
V71418	LPYFD-NH2	700361-48-4	LPYFD-NH2 is a pentapeptide that can inhibit the aggregation of Aβ(1-42).
V80619	LPYFD-NH2 TFA		LPYFD-NH2 TFA is a pentapeptide that can inhibit the aggregation of Aβ(1-42).
V71420	MCAAD-3	1625629-51-7	MCAAD-3 is a near-infrared Aβ imaging probe with BBB (blood-brain barrier) penetration.
V139518	mcK6A1		mcK6A1 is an amyloid β protein (Aβ) aggregation inhibitor that selectively binds to the 16KLVFFA21 fragment of Aβ42 to form an extended β-sheet structure, thereby inhibiting the formation of Aβ42 oligomers.
V139580	MEDI-1814		MEDI-1814 is a fully human IgG1 antibody that targets the C-terminus of Aβ42.
V119671	Merinetug	3024381-10-7	Merinetug is a humanized IgG1κ antibody that targets amyloid β/Aβ, with the corresponding isotype control being the human IgG1 kappa isotype control.
V104231	MeS-IMPY	955376-42-8	MeS-IMPY is a ligand for amyloid-β plaques.
V71441	Methyl tridecanoate	1731-88-0	Methyl tridecanoate moderately inhibits β-amyloid protein (β-amyloid) aggregation.
V109021	MG-H1	149204-50-2	MG-H1 is a ligand for the receptor for advanced glycation end products (RAGE) with a dissociation constant (Kd) of 4.12 nM.
V116752	Mivelsiran	2572991-83-2	Mivelsiran is a small interfering RNA (siRNA) that targets β-amyloid precursor protein (APP) and is used in Alzheimer's disease research.
V116747	Mivelsiran sodium		Mivelsiran sodium is a small interfering RNA (siRNA) that targets β-amyloid precursor protein (APP) and is used in Alzheimer's disease research.
V140013	Mivelsiran sodium scrambled negative control		The Mivelsiran sodium scrambled negative control is a negative control for Mivelsiran sodium with a scrambled sequence.