Beta Amyloid

ADC Related

ADC Antibody ADC Cytotoxin ADC Linker ADCs Drug-Linker Conjugates for ADC
Angiogenesis

5-alpha Reductase ALK Bcr-Abl BTK EGFR FAK FLT3 HER-2 HIF Src Syk VDA VEGFR
Anti-infection

Antibiotic Arenavirus Bacterial CMV EBV Enterovirus Filovirus Fungal Gli HBV HCV HCV Protease HIV HSV Influenza Virus Parasite RABV Reverse Transcriptase RSV SARS-CoV TMV Virus Protease
Apoptosis

Apoptosis ASK Bcl-2 Caspase c-Myc c-RET Cytohesin DAPK Ferroptosis FKBP IAP Mdm2 p53 PD-1 PD-L1 PERK PKD Ras RIP kinase ROS Survivin Thymidylate Synthase TNF Receptor TNFa TRADD
Autophagy

Autophagy LRRK2 Mitophagy OGA ULK
Cell Cycle

Antifolate APC Aurora Kinase BMI-1 CDK Chk c-Myc Eukaryotic Initiation Factor G-quadruplex HDAC HSP Kinesin LIMK Mad2 Microtubule(Tubulin) Mps1 Nucleoside Antimetabolite/Analog Nur77 p21 PAK PERK PFKFB PLK PPAR Ras Rho ROCK SRPK TOPK Topoisomerase Wee1
Cytoskeletal Signaling

Arp2 3 Complex Bcr-Abl Cardiac Myosin Dynamin Gap Junction Protein HSP Integrin Kinesin Microtubule Associated MLCK Myosin PAK TACC3 Wntbeta-catenin
DNA Damage

ATM(ATR) CRISPR(Cas9) DNA alkylator DNA Stain DNA(RNA) Synthesis GAK HDAC HSP Nucleoside Antimetabolite(Analog) OGG1 p97 PARG PARP RAD51 RNR Sirtuin SMN Telomerase Topoisomerase
Endocrinology & Hormones

5-alpha Reductase ACE Adrenergic Receptor Androgen Receptor Aromatase Estrogenprogestogen Receptor Glucocorticoid Receptor GPR Mineralocorticoid Receptor RAAS THR TSH Receptor
Epigenetics

AMPK Aurora Kinase DNA Methyltransferase Epigenetic Reader Domain EZH1 2 HDAC HIF Histone Acetyltransferase Histone Demethylase Histone Methyltransferase JAK MAT MicroRNA MLL Pim PKC Protein Arginine Deiminase Sirtuin Small Interfering RNA (siRNA) SMYD

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Beta Amyloid

As the primary component of the amyloid plaques seen in the brains of Alzheimer patients, amyloid- (A) refers to peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease. The amyloid precursor protein (APP), which is cut by specific enzymes to produce A, produces the peptides. Amyloid molecules can group together to create a variety of flexible, soluble oligomers.A amyloid-peptide buildup results from excessive A production or malfunctioning clearance mechanisms. Amyloid- forms diffuse and neuritic plaques in the parenchyma and blood vessels by self-aggregating into oligomers of various sizes. Strong synaptotoxins, proteasome inhibition, mitochondrial inhibition, alteration of intracellular Ca2+ levels, and induction of inflammatory processes are all characteristics of amyloid-oligomers and plaques. Neuronal dysfunction is also thought to be influenced by the loss of A's typical physiological functions.

Beta Amyloid related products

Cat No.	Product Name	CAS No.	Product Description
V134182	Donanemab (Mouse IgG2b)		Donanemab (Mouse IgG2b) is a chimeric antibody composed of a humanized variable region and a mouse IgG2b backbone.
V11347	Emrusolmin (Anle138b)	882697-00-9	Anle138b is a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.
V1315	EUK 134	81065-76-1	EUK 134 (EUK-134; EUK134), a synthetic and cell permeable superoxide dismutase (SOD)/catalase mimetic, is a novel antioxidant compound that exhibits potent antioxidant activities.
V135957	FITC-Ahx-β-Amyloid (1-42), (rat/mouse) tris		FITC-Ahx-β-Amyloid (1-42), (rat/mouse) tris is a fluorescently labeled (FITC) β-amyloid (1-42) (rat/mouse) product that can be used in Alzheimer's disease-related research, such as aggregation, fibrosis, cellular uptake, or imaging experiments.
V79435	FITC-β-Ala-β-Amyloid (25-35)		FITC-β-Ala-β-Amyloid (25-35) is a fluorescent product labeled by FITC and may be utilized in the research of AD/Alzheimer's disease.
V79436	FITC-β-Amyloid (25-35)		FITC-β-Amyloid (25-35) is FITC labeled β-Amyloid (25-35).
V71357	Fmoc-Ala-Glu-Asn-Lys-NH2	220701-06-4	Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase AEP inhibitory peptide that can inhibit the cleavage of amyloid precursor protein APP.
V2810	FPS-ZM1	945714-67-0	FPS-ZM1 is a potent and high-affinityRAGEspecific blocker with Kivalue of 25 nM.
V118674	GL-522	137407-62-6	GL-522 (4-sulfocalix[8]arene) is an Aβ42 inhibitor.
V71440	Glp-amyloid-β (3-40) peptide (human) (AβpE3-40)	161818-04-8	Glp-Amyloid-β (3-40) Peptide (human) (AβpE3-40) is a small amount of pyroglutamic acid-modified Aβ extracted from 24-month-old amyloid precursor protein transgenic mice.
V79396	Glutaminyl Cyclase Inhibitor 5	3033553-63-5	Glutaminyl Cyclase Inhibitor 5 (Compound 71) is a potent and specific inhibitor of human glutaminyl cyclase (hQC) with IC50 of 3.2 nM.
V87776	Glutaminyl Cyclase Inhibitor 6		Glutaminyl Cyclase Inhibitor 6 (compound BI-43) is a secretory glutaminyl cyclase (sQC) and golgi-resident glutaminyl cyclase (gQC) inhibitor with IC50 values of 0.012 and 0.040 µM, respectively.
V104260	Glutaminyl cyclases-IN-2		Glutamine cyclase-IN-2 (Compound 27) is a potent glutamine cyclase inhibitor with IC50 of 0.08 μM.
V115305	GLY-230	320777-05-7	GLY-230 is an orally active compound.
V136771	Glycerophosphorylethanolamine sodium	883288-78-6	Glycerophosphorylethanolamine sodium is an active phosphodiester metabolite of phosphatidylethanolamine.
V136912	Grape Skin Extract		Grape Skin Extract is a substance extracted from grape skins, and its components include polyphenols.
V136979	GSK-933776		GSK-933776 is a humanized antibody expressed in CHO cells that targets amyloid β/Aβ.
V114392	h-FTAA	1352477-26-9	h-FTAA is a luminescent conjugated oligothiophene (LCO) probe.
V79691	hAChE-IN-3	2983723-56-2	hAChE-IN-3 (compounds 5c) is a potent and BBB (blood-brain barrier) permeable (penetrable) inhibitor of AChE, BuChE, MAO-B-IN-1 and BACE-1 with IC50s of 0.44, 0.08, 5.15 and 1, respectively.
V79693	hAChE-IN-5		hAChE-IN-5 (compound 49) is a potent inhibitor of hAChE and hBuChE with IC50s of 0.17 μM and 0.17 μM, respectively.