As the primary component of the amyloid plaques seen in the brains of Alzheimer patients, amyloid- (A) refers to peptides of 36–43 amino acids that are crucially involved in Alzheimer's disease. The amyloid precursor protein (APP), which is cut by specific enzymes to produce A, produces the peptides. Amyloid molecules can group together to create a variety of flexible, soluble oligomers.A amyloid-peptide buildup results from excessive A production or malfunctioning clearance mechanisms. Amyloid- forms diffuse and neuritic plaques in the parenchyma and blood vessels by self-aggregating into oligomers of various sizes. Strong synaptotoxins, proteasome inhibition, mitochondrial inhibition, alteration of intracellular Ca2+ levels, and induction of inflammatory processes are all characteristics of amyloid-oligomers and plaques. Neuronal dysfunction is also thought to be influenced by the loss of A's typical physiological functions.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V147575 | β Amyloid (1-14), human | β Amyloid (1-14), human is a peptide fragment of β-amyloid protein (Aβ), obtained by hydrolyzing the Aβ1-40 peptides using the catalytic antibody light chain #7TR. | |
|
V71404 | β Amyloid (1-16) rat | 1123154-43-7 | β-Amyloid (1-16) rat is a β-amyloid peptide (Abeta), a metal-binding domain fragment of amyloid protein. |
|
V71435 | β Amyloid (1-39) | 115427-62-8 | β Amyloid (1-39) is an Aβ fragment. |
|
V71401 | β Amyloid (1-42) (scrambled) | 1678415-52-5 | β Amyloid (1-42) (scrambled) is a control of β-Amyloid (1-42), human TFA. |
|
V71375 | β Amyloid (11-42) | 157802-70-5 | β Amyloid (11-42) is an Aβ fragment. |
|
V71387 | β Amyloid (3-40) | 157884-70-3 | β Amyloid (3-40) is an Aβ fragment. |
|
V81799 | β Amyloid(17-28) human | β Amyloid(17-28) human is a β-amyloid peptide (Abeta), a lipid-induced amyloid core fragment. | |
|
V71436 | β Amyloid(28-35)human | 182945-56-8 | β Amyloid(28-35) human is a β-amyloid peptide (Abeta), a lipid-induced amyloid core fragment. |
|
V81806 | β-Amyloid (1-14),mouse,rat | β-Amyloid (1-14),mouse,rat is the 1-14 fragment of the Amyloid-β polypeptide. | |
|
V66652 | β-Amyloid (1-19) (acetate) | β-Amyloid (1-19) acetate is the acetate salt form of β-Amyloid (1-19) and consists of amino acid (AA)s 1-19 of β-Amyloid. | |
|
V66601 | β-Amyloid (1-20) (acetate) | β-Amyloid (1-20) acetate is the acetate salt form of β-Amyloid (1-20) and consists of amino acid (AA)s 1-20 of β-Amyloid. | |
|
V71421 | β-Amyloid (1-37) (human) | 186359-67-1 | β-Amyloid (1-37) (human) is highly correlated with AD/Alzheimer's disease Mental State Examination (MMSE) scores. |
|
V71412 | β-Amyloid (1-38) (Aβ (1-38); Aβ38) | 131438-74-9 | β-Amyloid (1-38) (Aβ (1-38); Aβ38) is an Aβ fragment. |
|
V147595 | β-Amyloid (1-38) TFA | β-Amyloid (1-38) TFA is a β-amyloid (Aβ) peptide. | |
|
V71388 | β-Amyloid (1-38), mouse, rat | 186359-66-0 | β-Amyloid (1-38), mouse, rat is a 38-amino acid (AA) polypeptide consisting of residues 1-38 of the β-Amyloid peptide. |
|
V57783 | β-Amyloid (1-40), FAM-labeled | 1678416-08-4 | β-Amyloid (1-40), FAM-labeled is a FAM fluorescently labeled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm). |
|
V81807 | β-Amyloid (1-40), FAM-labeled TFA | β-Amyloid (1-40), FAM-labeled TFA is a FAM fluorescently labeled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm). | |
|
V147597 | β-Amyloid (1-40), HFIP-treated TFA | β-Amyloid (1-40), HFIP-treated TFA refers to β-amyloid protein (1-40) treated with HFIP. | |
|
V66370 | β-Amyloid (1-42), (rat/mouse) (TFA) (Amyloid β-peptide (1-42) (rat/mouse) TFA) | β-Amyloid (1-42), (rat/mouse) TFA is a 42-amino-acid polypeptide that is toxic to hippocampal slices and may be utilized in AD/Alzheimer's disease study. | |
|
V87771 | β-Amyloid (1-42), human TFA | β-Amyloid (1-42), human TFA (Amyloid β-Peptide (1-42) (human) TFA) is a 42-amino acid peptide that plays a key role in the pathogenesis of Alzheimer's disease. |