Opioid ligands are a class of G protein-coupled receptors known as opioid receptors. Dynorphins, enkephalins, endorphins, endomorphins, and nociceptin are examples of endogenous opioids. There are many opioid receptors in the brain, as well as in the spinal cord and digestive system. The body has molecules or sites called opioid receptors that are triggered by opioid substances. Opioid receptors prevent impulses from traveling along excitatory pathways in the human body.The serotonin, catecholamine, and substance P pathways are some of these pathways, and they are all thought to play a role in pain perception and feelings of wellbeing. Mu, delta, and kappa receptors are additional subclassifications of opioid receptors. While each class has its own unique way of acting, they all have some fundamental things in common. The potassium pump mechanism, which is present on the plasma membrane of most cells, powers them all.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
|
V128420 | AH 8507 | 41805-63-4 | AH 8507 is an analogue of AH 7563. |
|
V107038 | AH 8529 | 41805-00-9 | AH 8529 is an oral opioid compound. |
|
V107037 | AH 8532 | 786581-55-3 | AH 8532 is an opioid with analgesic effects. It can inhibit the writhing reaction induced by benzoquinone in mice, with an oral ED50 value of 16 mg/kg. |
|
V103010 | AH-8533 | 759397-79-0 | AH-8533 is an opioid. |
|
V103203 | Allyphenyline oxalate | 1092984-08-1 | Allyl phenyl oxalate (Compound 9) can enhance the analgesic effect of morphine. The pKi values of allyl phenyl oxalate for α2A, α2B and α2C are 7.24, 6.47 and 7.07, respectively. |
|
V102759 | Alvimopan metabolite hydrochloride | 170098-43-8 | Alvimopan metabolite hydrochloride is a peripherally restricted opioid receptor antagonist that inhibits the amplitude of electrically evoked contractions and spontaneous mechanical activity in the guinea pig ileum. |
|
V114586 | Amdakefalin | 2253747-71-4 | Amdakefalin is a μ and δ opioid receptor agonist with analgesic effects. |
|
V93108 | Anilopam | 53716-46-4 | Anilopam is an opioid analgesic that belongs to the benzazepine class and is an opioid receptor agonist. |
|
V69937 | Anrikefon acetate (HSK21542 acetate) | 2584931-05-3 | Anrikefon (HSK21542) acetate is a kappa opioid receptor agonist (activator) with pain-relief effects. |
|
V104966 | AP-238 | 140924-11-4 | AP-238 is a novel synthetic opioid (NSO) that acts as an agonist at the μ-opioid receptor (MOR) with an EC50 of 248 nM. |
|
V89805 | AR-M 1000390 | 209808-01-5 | AR-M 1000390 is a potent and selective δ opioid receptor agonist with EC50 of 7.2±0.9 nM. |
|
V84961 | AT-035 | 2099680-55-2 | |
|
V69926 | AT-121 | 2099681-31-7 | AT-121 is a bifunctional nociception and mu opioid receptor agonist/activator with Kis of 3.67 and 16.49 nM respectively. |
|
V69930 | AT-121 hydrochloride | 2099681-71-5 | AT-121 HCl is a bifunctional nociception and mu opioid receptor agonist/activator with Kis of 3.67 and 16.49 nM respectively. |
|
V85133 | AT-127 | 2099680-72-3 | |
|
V86695 | Atoxifent | Atoxifent is a μ-opioid receptor agonist (EC50=0.39 nM), which is found in brain regions that control pain, mood, habit learning, and cognition. | |
|
V69924 | BAN ORL 24 free base | 475150-69-7 | BAN ORL 24 free base is a NOP receptor antagonist. |
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V4694 | BAN-ORL-24 HCl | 1401463-54-4 | BAN ORL 24 is a novel, potent and selective NOP (nociceptin/orphanin FQ (N/OFQ) peptide receptor) receptor antagonist with IC50 values of 0.27, 2500, 6700 and > 10000 nM for NOP, κ-, μ- and δ-receptors respectively. |
|
V86698 | Bilaid A | 2393865-97-7 | Bilaid A is a μ-opioid receptor agonist extracted from Penicillium with a Ki value of 3.1 μM. |
|
V88933 | Bilaid A1e | 2393866-02-7 | Bilaid A1e (Compound 1e) is a tetrapeptide agonist of the µ-opioid receptor (Ki = 750 nM). |
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