Opioid ligands are a class of G protein-coupled receptors known as opioid receptors. Dynorphins, enkephalins, endorphins, endomorphins, and nociceptin are examples of endogenous opioids. There are many opioid receptors in the brain, as well as in the spinal cord and digestive system. The body has molecules or sites called opioid receptors that are triggered by opioid substances. Opioid receptors prevent impulses from traveling along excitatory pathways in the human body.The serotonin, catecholamine, and substance P pathways are some of these pathways, and they are all thought to play a role in pain perception and feelings of wellbeing. Mu, delta, and kappa receptors are additional subclassifications of opioid receptors. While each class has its own unique way of acting, they all have some fundamental things in common. The potassium pump mechanism, which is present on the plasma membrane of most cells, powers them all.
| Structure | Cat No. | Product Name | CAS No. | Product Description |
|---|---|---|---|---|
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V69899 | UFP-101 | 849024-68-6 | UFP-101 is a specific and competitive NOP receptor antagonist (inhibitor) with pKi of 10.24. |
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V76390 | UFP-101 TFA | UFP-101 TFA is a specific and competitive NOP receptor antagonist (inhibitor) with pKi of 10.24. | |
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V69944 | ZP 120C | 383123-18-0 | ZP 120C is a potent ORL1 receptor partial agonist. |
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V100612 | α-Endorphin (human) | 59004-96-5 | Alpha-endorphin (human) is a neuropeptide that acts on the central nervous system (CNS) and the peripheral nervous system (PNS). |
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V86692 | β-Chlornaltrexamine dihydrochloride | 67025-98-3 | β-Chlornaltrexamine dihydrochloride (β-CNA dihydrochloride) is a potent long-term opioid receptor blocker. |
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V69936 | β-Endorphin (1-27) (human) | 76622-84-9 | β-Endorphin (1-27) (human) is an opioid antagonist that binds to μ-, δ-, and κ-opioid receptors with Kis of 5.31, 6.17, and 39.82 nM, respectively. |
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V69969 | β-Endorphin (6-31), human (β-EP (6-31), human) | 77761-27-4 | β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. |
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V69906 | β-Endorphin(rat) | 309246-19-3 | β-Endorphin (rat) is an endogenous opioid neuropeptide and peptide hormone. |
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V65820 | β-Endorphin, equine TFA | β-Endorphin, equine TFA is an endogenous opioid peptide with strong affinity for μ and δ opioid receptors (μ/δ opioid receptors). | |
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V109157 | β-Funaltrexamine | 72782-05-9 | β-Fenadrolamine (β-FNA) is a selective, irreversible μ-opioid receptor antagonist with anti-inflammatory and neuroprotective effects. |
![β-Lipotropin (60-65) (β-LPH (60-65); [Arg0] Met-Enkephalin)](http://www.invivochem.com/upload/1124/V69919.png)
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V69919 | β-Lipotropin (60-65) (β-LPH (60-65); [Arg0] Met-Enkephalin) | 60117-19-3 | β-Lipotropin (60-65) (β-LPH (60-65)) is an opioid peptide and a potent opioid agonist. |
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V69942 | β-Lipotropin (61-69) (β-LPH (61-69)) | 59481-79-7 | β-Lipotropin (61-69) is a potent opioid agonist. |
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V85004 | μ/κ/δ opioid receptor agonist 1 | ||
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V85821 | σ1 Receptor/μ Opioid receptor modulator 2 | 3009018-61-2 | |
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V19863 | Difelikefalin | 1024828-77-0 | Difelikefalin (MR-13A9; CR-845; MR-13A-9; trade name Korsuva) is a novel, peripherally specific, and potent kappa opioid receptor agonist approved in 2021 asan analgesic opiod peptide for the treatment of moderate-to-severe itching. |
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V1274 | Nitrendipine (BAY-E-5009) | 39562-70-4 | Nitrendipine (BAY-E5009; BAY E-5009; Bayotensin; Bayotensin, Baypress, Nidrel, Deiten) is a potent dihydropyridine (DHP) calcium channel blocker (CCB) with antihypertensive effects. |
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V29494 | Porcine dynorphin A(1-13) | 72957-38-1 | Porcine dynorphin A (1-13) is a potent endogenous κ opioid receptor agonist (activator) that relieves pain at physiological concentrations. |
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V1281 | Trimebutine | 39133-31-8 | Trimebutine (Mebutin; Debridat; Polibutin; Modulon; Dromostat; Ibutin; Polibutin; TM 906; Trimedat)is a potent agonist of peripheral mu, kappa and delta(μ,κ, andδ)opioid receptors. |
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V1277 | Lomerizine HCl (KB-2796) | 101477-54-7 | Lomerizine HCl (KB-2796; Migsis; KB2796; KB 2796), the dihydrochloride salt of Lomerizine, is a diphenylpiperazine-based, relatively new and potent L- and T-type CCB/calcium channel blocker used for the treatment of migraine. |
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V1278 | Racecadotril (acetorphan) | 81110-73-8 | Racecadotril (also called acetorphan) is a potent and peripherally acting enkephalinase inhibitor used as an antidiarrheal medication. |
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